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This paper is in the following e-collection/theme issue:

#xBioengineering (4) Pilot studies (non-ehealth) (240) #xNeurology (8) Cellular and tissue engineering (4) Biomaterials (18) #xAnimal Behavior and Cognition (4) #xNeuroscience (3) Translational Research in Biomedical Engineering (3)

Published on in Vol 4 (2026)

Preprints (earlier versions) of this paper are available at https://www.biorxiv.org/content/10.1101/2025.03.20.644358v1, first published .
Computer screen showing TBI study flowchart: Create TBI, implant scaffold, assess outcome.

Material-Driven Therapeutics to Establish a Penetrating Traumatic Brain Injury Rat Model and Implantation of a 3D-Printed Scaffold: Pre-Experimental Pilot Study

Material-Driven Therapeutics to Establish a Penetrating Traumatic Brain Injury Rat Model and Implantation of a 3D-Printed Scaffold: Pre-Experimental Pilot Study

Authors of this article:

Meaghan E Harley-Troxell1 Author Orcid Image ;   Michelle Dennis2 Author Orcid Image ;   Madhu Dhar1 Author Orcid Image
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Meaghan E Harley-Troxell   1 , PhD ;   Michelle Dennis   2 , PhD ;   Madhu Dhar   1 , PhD

1 Tissue Engineering and Regenerative Medicine Lab, LACS, College of Veterinary Medicine, University of Tennessee at Knoxville, Knoxville, TN, United States

2 Biomedical and Diagnostic Sciences Department, College of Veterinary Medicine, University of Tennessee at Knoxville, Knoxville, TN, United States

Corresponding Author:

  • Meaghan E Harley-Troxell, PhD
  • Tissue Engineering and Regenerative Medicine Lab, LACS, College of Veterinary Medicine
  • University of Tennessee at Knoxville
  • 2407 River Drive
  • Knoxville, TN 37996
  • United States
  • Phone: 1 (865) 974-5703
  • Email: mharley-troxell@som.umaryland.edu