JMIRx Bio
An overlay journal for BioRxiv preprints with post-review manuscript marketplace (What is JMIRx?).
Editor-in-Chief:
Amy Schwartz, MSc, PhD, Scientific Editor at JMIR Publications, Ontario, Canada
Recent Articles

The Japanese archipelago during the Jōmon period (14,000 to 800 cal BC), when people engaged mainly in hunting and gathering and experienced relatively more severe climate changes, was an important prehistoric period for investigating how people reacted to environmental fluctuations in human evolutionary history. Anthropologists have extensively discussed the population history in the Jōmon period of the Japanese archipelago via their morphological variations. Some have supported the notion of relative morphological uniformity within the Jōmon population, which could be sustained by widespread population interactions, although others have claimed that spatiotemporal morphological differences (especially geographical clines) may exist to some extent.

Cholesterol biosynthesis is a critical pathway in cellular metabolism, with 3- hydroxy-3-methylglutaryl coenzyme-A reductase (HMGR) catalyzing its committed step. The inhibition of HMGR has been widely explored as a therapeutic target for managing hypercholesterolemia, and statins are the most commonly used competitive inhibitors. However, the search for novel, natural inhibitors of HMGR is still a vital area of research, especially in light of the adverse effects of the prolonged use of statins. Cochlospermum planchonii and Cochlospermum tinctorium are medicinal plants traditionally used in West Africa to treat metabolic disorders, including dyslipidemia, but the specific bioactive compounds responsible for these effects are currently poorly characterized.

Ticks are well-known ectoparasites of domestic animals, causing significant economic losses and playing a crucial role in the transmission of pathogens within the livestock industry worldwide, including in Iran. Understanding the distribution and diversity of ticks is essential for effective control strategies, especially in regions like Tehran province, where livestock plays a vital role in the economy.
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